File:Age-Dependent-Cell-Trafficking-Defects-in-Draining-Lymph-Nodes-Impair-Adaptive-Immunity-and-Control-ppat.1005027.s009.ogv
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Age-Dependent-Cell-Trafficking-Defects-in-Draining-Lymph-Nodes-Impair-Adaptive-Immunity-and-Control-ppat.1005027.s009.ogv (Ogg Theora video file, length 7.3 s, 652 × 599 pixels, 417 kbps, file size: 372 KB)
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DescriptionAge-Dependent-Cell-Trafficking-Defects-in-Draining-Lymph-Nodes-Impair-Adaptive-Immunity-and-Control-ppat.1005027.s009.ogv |
English: Intravital microscopy showing differential movement of adoptively transferred naïve CD4 + T cells from adult and old mice in explanted LN. Naïve CD4+ T cells from adult and old mice were sorted, differentially labeled with fluorescent dyes (adult = green; old = blue) and adoptively transferred into adult mice that had been infected subcutaneously with WNV-KUN 48 hours earlier. Six hours later, the DLN was explanted and evaluated by intravital microscopy. Measurements of velocity and distance movement by individual naïve CD4+ T cells (see Fig 4and S4 Fig) were obtained from these videos. One representative experiment of several independent trials is shown. The time of analysis and scale bar are indicated. |
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Source | S3 Movie from Richner J, Gmyrek G, Govero J, Tu Y, van der Windt G, Metcalf T, Haddad E, Textor J, Miller M, Diamond M (2015). "Age-Dependent Cell Trafficking Defects in Draining Lymph Nodes Impair Adaptive Immunity and Control of West Nile Virus Infection". PLOS Pathogens. DOI:10.1371/journal.ppat.1005027. PMID 26204259. PMC: 4512688. | ||
Author | Richner J, Gmyrek G, Govero J, Tu Y, van der Windt G, Metcalf T, Haddad E, Textor J, Miller M, Diamond M | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 21:38, 28 July 2015 | 7.3 s, 652 × 599 (372 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Intravital microscopy showing differential movement of adoptively transferred naïve CD4 + T cells from adult and old mice in explanted LN. |
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Author | Richner J, Gmyrek G, Govero J, Tu Y, van der Windt G, Metcalf T, Haddad E, Textor J, Miller M, Diamond M |
Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | Naïve CD4+ T cells from adult and old mice were sorted, differentially labeled with fluorescent dyes (adult |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2015-07-23 |