File:Tyrosine-Binding-Protein-Sites-Regulate-the-Intracellular-Trafficking-and-Processing-of-Amyloid-pone.0161445.s008.ogv
From Wikimedia Commons, the free media repository
Jump to navigation
Jump to search
No higher resolution available.
Tyrosine-Binding-Protein-Sites-Regulate-the-Intracellular-Trafficking-and-Processing-of-Amyloid-pone.0161445.s008.ogv (Ogg Theora video file, length 12 s, 466 × 463 pixels, 1.47 Mbps, file size: 2.09 MB)
File information
Structured data
Captions
Summary[edit]
DescriptionTyrosine-Binding-Protein-Sites-Regulate-the-Intracellular-Trafficking-and-Processing-of-Amyloid-pone.0161445.s008.ogv |
English: DCP-LA treatment disrupts APP trafficking to the lysosome. SN56 cells were transiently transfected with βAPP-paGFP (green), LAMP1-mRFP (lysosome marker, red), and GalT-CFP (Golgi marker, blue) and treated with 500nM DCP-LA. APP was photo-activated in the Golgi (blue) with 405nm light, alternating with imaging for 15 minutes (indicated by green word ‘Photo-activating’). White circles in the video denote photo-activation ROIs in the Golgi. Cells were then chased imaging every 30 seconds for the indicated time. |
||
Date | |||
Source | S7 Video from Tam J, Cobb M, Seah C, Pasternak S (2016). "Tyrosine Binding Protein Sites Regulate the Intracellular Trafficking and Processing of Amyloid Precursor Protein through a Novel Lysosome-Directed Pathway". PLOS ONE. DOI:10.1371/journal.pone.0161445. PMID 27776132. PMC: 5077117. | ||
Author | Tam J, Cobb M, Seah C, Pasternak S | ||
Permission (Reusing this file) |
This file is licensed under the Creative Commons Attribution 4.0 International license.
|
||
Provenance InfoField |
|
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 09:01, 31 January 2017 | 12 s, 466 × 463 (2.09 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
You cannot overwrite this file.
File usage on Commons
The following page uses this file:
Transcode status
Update transcode statusMetadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Short title | DCP-LA treatment disrupts APP trafficking to the lysosome. |
---|---|
Author | Tam J, Cobb M, Seah C, Pasternak S |
Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | SN56 cells were transiently transfected with βAPP-paGFP (green), LAMP1-mRFP (lysosome marker, red), and GalT-CFP (Golgi marker, blue) and treated with 500nM DCP-LA. APP was photo-activated in the Golgi (blue) with 405nm light, alternating with imaging for 15 minutes (indicated by green word ‘Photo-activating’). White circles in the video denote photo-activation ROIs in the Golgi. Cells were then chased imaging every 30 seconds for the indicated time. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2016-10-24 |