File:Lysosomal-Interaction-of-Akt-with-Phafin2-A-Critical-Step-in-the-Induction-of-Autophagy-pone.0079795.s007.ogv

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Lysosomal-Interaction-of-Akt-with-Phafin2-A-Critical-Step-in-the-Induction-of-Autophagy-pone.0079795.s007.ogv(Ogg Theora video file, length 16 s, 170 × 170 pixels, 40 kbps, file size: 79 KB)

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English: Mutant Phafin2 showed no granular patterns in the cytosol and perinuclear accumulation of the Akt-Phafin2 complex. S2: By contrast, PI(3)P interacting defective mutant Phafin2 (R53C, R171A, and R172A), which did not bind to PI(3)P (Fig. 5A), displayed almost no granular patterns in the cytosol nor perinuclear accumulation of the Akt-Phafin2 complex determined by the absence of the enlarged perinuclear protein aggregates after induction of autophagy in BiFC analysis.
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Source Movie S2 from Matsuda-Lennikov M, Suizu F, Hirata N, Hashimoto M, Kimura K, Nagamine T, Fujioka Y, Ohba Y, Iwanaga T, Noguchi M (2014). "Lysosomal Interaction of Akt with Phafin2: A Critical Step in the Induction of Autophagy". PLOS ONE. DOI:10.1371/journal.pone.0079795. PMC: 3885392.
Author Matsuda-Lennikov M, Suizu F, Hirata N, Hashimoto M, Kimura K, Nagamine T, Fujioka Y, Ohba Y, Iwanaga T, Noguchi M
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Date/TimeThumbnailDimensionsUserComment
current22:27, 11 January 201416 s, 170 × 170 (79 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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