File:Kupffer-Cells-Hasten-Resolution-of-Liver-Immunopathology-in-Mouse-Models-of-Viral-Hepatitis-ppat.1002061.s009.ogv

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Kupffer-Cells-Hasten-Resolution-of-Liver-Immunopathology-in-Mouse-Models-of-Viral-Hepatitis-ppat.1002061.s009.ogv ‎(Ogg Theora video file, length 23 s, 320 × 238 pixels, 137 kbps, file size: 390 KB)

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English: PGK-GFP 1.3.32 HBV chimeric mice in which KCs and circulating white blood cells express GFP (green) were subjected to liver intravital microscopy. The movie depicts periportal liver sinusoids in a representative mouse that was infused 15 minutes earlier with 108 rhodamine-labeled beads (red) and 5 minutes earlier with 106 Hoechst-labeled HBV-specific effector CD8 T cells (blue). The movie shows an example of a virus-specific effector CD8 T cell arresting in close proximity and transiently coming in contact with a KC. Analysis of 30 minutes movies derived from 6 independent chimeric mice showed 30% of visualized HBV-specific effector CD8 T cells interacting with KCs (mean interaction time of 5±1 second). Scale bar represents 50 µm.
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Source Video S1 from Sitia G, Iannacone M, Aiolfi R, Isogawa M, van Rooijen N, Scozzesi C, Bianchi M, von Andrian U, Chisari F, Guidotti L (2011). "Kupffer Cells Hasten Resolution of Liver Immunopathology in Mouse Models of Viral Hepatitis". PLOS Pathogens. DOI:10.1371/journal.ppat.1002061. PMID 21655107. PMC: 3107209.
Author Sitia G, Iannacone M, Aiolfi R, Isogawa M, van Rooijen N, Scozzesi C, Bianchi M, von Andrian U, Chisari F, Guidotti L
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Date/TimeThumbnailDimensionsUserComment
current14:14, 17 November 201223 s, 320 × 238 (390 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 240P Not ready Unknown status
Streaming 240p (VP9) 70 kbps Completed 04:42, 13 January 2024 4.0 s
WebM 360P 74 kbps Completed 19:21, 1 December 2023 2.0 s
Streaming 144p (MJPEG) 575 kbps Completed 09:44, 17 November 2023 1.0 s

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