File:In-Vivo-Imaging-Reveals-Distinct-Inflammatory-Activity-of-CNS-Microglia-versus-PNS-Macrophages-in-a-pone.0017910.s003.ogv

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In-Vivo-Imaging-Reveals-Distinct-Inflammatory-Activity-of-CNS-Microglia-versus-PNS-Macrophages-in-a-pone.0017910.s003.ogv ‎(Ogg Theora video file, length 19 s, 507 × 206 pixels, 418 kbps, file size: 946 KB)

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English: Enhanced response and early migration of microglia towards a single axon transection in the lateral column of a preclinical SOD1G93A mouse. This video sequence (195-minute) lasts from 15 minutes before to 180 minutes after a laser-induced axonal transection in a 60-day-old mutant mouse. It shows an increased response of microglia towards the injured site (note the autofluorescence; arrow). The response comprised a rapid movement of cell soma starting within a few minutes after the injury. An enhanced and early (starting within the first hour after the injury) phagocytic activity of microglia, indicated by numerous engulfments within and around the injured site, could also be observed. The frame rate of the video is about 90 seconds per MIP. Scale bar, 20 µm.
Date
Source Video S3 from Dibaj P, Steffens H, Zschuntzsch J, Nadrigny F, Schomburg E, Kirchhoff F, Neusch C (2011). "In Vivo Imaging Reveals Distinct Inflammatory Activity of CNS Microglia versus PNS Macrophages in a Mouse Model for ALS". PLOS ONE. DOI:10.1371/journal.pone.0017910. PMID 21437247. PMC: 3060882.
Author Dibaj P, Steffens H, Zschuntzsch J, Nadrigny F, Schomburg E, Kirchhoff F, Neusch C
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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.
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Date/TimeThumbnailDimensionsUserComment
current21:58, 28 May 201319 s, 507 × 206 (946 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 240P 134 kbps Completed 15:21, 29 August 2018 7.0 s
Streaming 240p (VP9) 135 kbps Completed 07:23, 5 December 2023 1.0 s
WebM 360P Not ready Unknown status
Streaming 144p (MJPEG) 332 kbps Completed 10:51, 15 November 2023 1.0 s

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