File:Cellular-Contractility-Requires-Ubiquitin-Mediated-Proteolysis-pone.0006155.s011.ogv

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search

Cellular-Contractility-Requires-Ubiquitin-Mediated-Proteolysis-pone.0006155.s011.ogv ‎(Ogg Theora video file, length 8.2 s, 450 × 375 pixels, 1.75 Mbps, file size: 1.71 MB)

Captions

Captions

Add a one-line explanation of what this file represents

Summary[edit]

Description
English: Neddylation is upstream of the RhoA pathway. E36-ts41 cells were transiently transfected with constitutively active form of RhoA Q63L fused to GFP(caRhoA-GFP), grown at 39.5°C and treated with nocodazole. While the non-transfected control cell on the left panel did not contract (see also movie 9E) the transfected cell on the right panel vigorously contracted for over 14 hours. This indicates that the neddylation process required for contractility is upstream to the RhoA signaling pathway. Moreover, this suggests that prolong blocking of neddylation does not result in ATP depletion or in over activation Myosin phosphatase.
Date
Source Movie S10 from Cinnamon Y, Feine O, Hochegger H, Bershadsky A, Brandeis M (2009). "Cellular Contractility Requires Ubiquitin Mediated Proteolysis". PLOS ONE. DOI:10.1371/journal.pone.0006155. PMID 19597551. PMC: 2705188.
Author Cinnamon Y, Feine O, Hochegger H, Bershadsky A, Brandeis M
Permission
(Reusing this file)
w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 2.5 Generic license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
PLOS
PLOS
This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
Provenance
InfoField
This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.
WikiProject Open Access
WikiProject Open Access

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current22:08, 21 November 20128.2 s, 450 × 375 (1.71 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

You cannot overwrite this file.

There are no pages that use this file.

Transcode status

Update transcode status
Format Bitrate Download Status Encode time
VP9 360P 393 kbps Completed 12:54, 21 August 2018 11 s
Streaming 360p (VP9) 393 kbps Completed 01:03, 25 January 2024 0.0 s
VP9 240P 165 kbps Completed 12:54, 21 August 2018 5.0 s
Streaming 240p (VP9) 165 kbps Completed 20:17, 5 December 2023 1.0 s
WebM 360P 508 kbps Completed 22:09, 21 November 2012 9.0 s
Streaming 144p (MJPEG) 983 kbps Completed 23:41, 1 November 2023 1.0 s

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:Cellular-Contractility-Requires-Ubiquitin-Mediated-Proteolysis-pone.0006155.s011.ogv&oldid=852260865"