File:Celiac disease.webm

The information in this video is inaccurate and outdated.

It focuses on celiac disease and non-celiac gluten sensitivity as simple digestive diseases, but:

«Celiac disease (CD) is a chronic, multiple-organ autoimmune disease that affects the small intestine in genetically predisposed children and adults.» (1)

«CD is an immune-mediated systemic disorder elicited by gluten and related prolamines in genetically susceptible individuals and characterised by the presence of a variable combination of gluten-dependent clinical manifestations» (2)

«The abnormal immunological response elicited by gluten-derived proteins can lead to the production of several different autoantibodies, which affect different systems.» (3)

«Presentation of CD with malabsorptive symptoms or malnutrition is now the exception rather than the rule» (4)

«The most important obstacle to implementing the recommendations is poor awareness of celiac disease by patients and physicians. Among gastroenterologists, there is a sense that celiac disease does not require follow-up by a specialized physician after diagnosis and may be considered a minor condition in comparison with irritable bowel disease (IBD) and inflammatory bowel syndrome (IBS).(...) There is an urgent need to increase awareness among primary-care physicians and pediatricians about the wide diversity of clinical manifestations.» (1)

«That gluten sensitivity is regarded as principally a disease of the small bowel is a historical misconception» (5)

1. World Gastroenterology Organisation Global Guidelines (WGO). "Celiac disease". (2016).

2. Husby S, Koletzko S, Korponay-Szabó IR, Mearin ML, Phillips A, Shamir R, Troncone R, Giersiepen K, Branski D, Catassi C, Lelgeman M, Mäki M, Ribes-Koninckx C, Ventura A, Zimmer KP, ESPGHAN Working Group on Coeliac Disease Diagnosis; ESPGHAN Gastroenterology Committee; European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (2012). "European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease" . J Pediatr Gastroenterol Nutr. 54 (1): 136–60.

3. Lundin KE, Wijmenga C (2015). "Coeliac disease and autoimmune disease-genetic overlap and screening". Nat Rev Gastroenterol Hepatol. 12 (9): 507–15.

4. Newnham ED (2017). "Coeliac disease in the 21st century: paradigm shifts in the modern age". J Gastroenterol Hepatol (Review). 32 Suppl 1: 82–85.