File:BMP, Wnt, and c-Kit signaling are activated in melanocytes in the hair bulb, but not in melanocyte stem cell population at the bulge region..jpg

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BMP,_Wnt,_and_c-Kit_signaling_are_activated_in_melanocytes_in_the_hair_bulb,_but_not_in_melanocyte_stem_cell_population_at_the_bulge_region..jpg ‎(500 × 335 pixels, file size: 94 KB, MIME type: image/jpeg)

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English: Skin sections from Dct-LacZ transgenic mice were stained with antibody against either phosphorylated Smad1/5/8, Lef1, c-Kit, or phosphorylated MEK1/2 (shown in green). Melanoblasts/melanocytes in the hair bulb or the bulge region are visualized by anti-LacZ antibody (shown in red). Melanocytes in the hair bulb are positively stained with these antibodies, indicating that BMP, c-Kit, and Wnt signaling pathways are activated in these cells. In contrast, none of these markers are detectable in the bulge melanoblasts, suggesting that these signaling pathways may not be implicated in melanocyte stem cell regulation.
Date Published June 30, 2009.
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StemBook Figure 5 BMP, Wnt, and c-Kit signaling are activated in melanocytes in the hair bulb, but not in melanocyte stem cell population at the bulge region.

  • Osawa,M., Melanocyte stem cells (June 30, 2009), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.46.1, http://www.stembook.org.
Author Osawa,M., Melanocyte stem cells (June 30, 2009), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.46.1, http://www.stembook.org.
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current18:38, 5 April 2013Thumbnail for version as of 18:38, 5 April 2013500 × 335 (94 KB)Smallbot (talk | contribs)Uploading CC-BY images from the the StemBook http://www.stembook.org/ 23/173

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