File:An-Intrinsically-Disordered-Region-of-the-Adenovirus-Capsid-Is-Implicated-in-Neutralization-by-pone.0061571.s005.ogv
An-Intrinsically-Disordered-Region-of-the-Adenovirus-Capsid-Is-Implicated-in-Neutralization-by-pone.0061571.s005.ogv (Ogg multiplexed audio/video file, Theora/Vorbis, length 22 s, 640 × 480 pixels, 3.43 Mbps overall, file size: 9.14 MB)
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DescriptionAn-Intrinsically-Disordered-Region-of-the-Adenovirus-Capsid-Is-Implicated-in-Neutralization-by-pone.0061571.s005.ogv |
English: MDFF simulation of defensin-resistant HAdV chimera, Ad5.PB/GYAR, in complex with defensin. MDFF frames from a 100-picosecond simulation show the short RGD-containing penton base loops (white) do not envelop the defensin molecules as extensively as observed for the defensin-sensitive HAdV chimera. The last frame shows the hydrophobic and positively charged fiber sequence (18-GYAR-21), which is correlated with defensin resistance, in a sphere representation. |
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Source | Movie S2 from Flatt J, Kim R, Smith J, Nemerow G, Stewart P (2013). "An Intrinsically Disordered Region of the Adenovirus Capsid Is Implicated in Neutralization by Human Alpha Defensin 5". PLOS ONE. DOI:10.1371/journal.pone.0061571. PMC: 3631211. | ||
Author | Flatt J, Kim R, Smith J, Nemerow G, Stewart P | ||
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current | 00:30, 27 April 2013 | 22 s, 640 × 480 (9.14 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Flatt J, Kim R, Smith J, Nemerow G, Stewart P |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | MDFF simulation of defensin-resistant HAdV chimera, Ad5.PB/GYAR, in complex with defensin. MDFF frames from a 100-picosecond simulation show the short RGD-containing penton base loops (white) do not envelop the defensin molecules as extensively as observed for the defensin-sensitive HAdV chimera. The last frame shows the hydrophobic and positively charged fiber sequence (18-GYAR-21), which is correlated with defensin resistance, in a sphere representation. |
Software used | |
Date and time of digitizing | 2013 |
Language | English |
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2013
application/ogg
a2c0e3612eabaa7f535d19c343089cce8caf5aa2
9,585,004 byte
22.35065759637188 second
480 pixel
640 pixel
- Biophysical simulations
- Macromolecular assemblies
- Videos of bioinformatics
- Macromolecular structure analysis
- Macromolecular complex analysis
- Videos of protein structures
- Innate immunity
- Videos of viral structure
- Host-pathogen interactions
- Videos of computational chemistry
- Molecular dynamics simulation
- Media from PLOS ONE
- Adenoviridae