File:Viruses-13-00435-g004-B.png
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Captions
Captions
Discontinuous and continuous transcription of torovirus (ToV).
Summary[edit]
| Description |
English: Discontinuous and continuous transcription of ToV. Model of structure-driven discontinuous (left) and continuous (right) transcription of ToV. In sg mRNA2, nascent (-) RNA synthesis is terminated by the hairpin (HP) structure and base pairing between homologous regions (blue), followed by L-TRS (green) and HP, promotes the template switch. After switching, the 5’ genome-derived sequence including a short leader (red) and L-TRS and additional nucleotides are added to nascent (-) RNA, resulting in complete (-) sg RNA synthesis. In sg mRNA 3-5, semiconserved sequences in the genome, CACN3-4CUUUAGA (yellow and green) including B-TRS (green) act as a termination signal, and complete (-) sg RNA synthesis is terminated at this region and is then detached from genome. (+) sg mRNA contains ACN3-4CUUUAGA at the 5’-end (without the C residue of the 5’-genome). A small portion of mRNA 5 contains a leader sequence that is subjected to discontinuous transcription. |
| Date | |
| Source | Ujike, M.; Taguchi, F. Recent Progress in Torovirus Molecular Biology. Viruses 2021, 13, 435. https://doi.org/10.3390/v13030435 |
| Author | Makoto Ujike and Fumihiro Taguchi |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 13:35, 22 June 2021 | | 2,926 × 2,050 (1.03 MB) | Guest2625 (talk | contribs) | Uploaded a work by Makoto Ujike and Fumihiro Taguchi from Ujike, M.; Taguchi, F. Recent Progress in Torovirus Molecular Biology. Viruses 2021, 13, 435. https://doi.org/10.3390/v13030435 with UploadWizard |
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