File:Viruses-13-00435-g004-A.png

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Discontinuous and continuous transcription of coronavirus (CoV).

Summary[edit]

Description
English: Discontinuous and continuous transcription of CoV. Model of TRS-driven discontinuous transcription of CoV. (-) RNA synthesis (light grey) initiates at the 3’-end of the genome and is terminated or attenuated when the replication and transcription complex (light blue circle) encounters B-TRS (in orange). The discontinuous step is driven by base-pairing between the anti-B-TRS and L-TRS within the hairpin, resulting in template switch from nascent (-) RNA to the leader. Next, (-) RNA synthesis re-initiates and a leader sequence (red) is added. This complete (-) sg RNA in turn serves as a template for (+) sg mRNAs.
Date
Source Ujike, M.; Taguchi, F. Recent Progress in Torovirus Molecular Biology. Viruses 2021, 13, 435. https://doi.org/10.3390/v13030435
Author Makoto Ujike and Fumihiro Taguchi

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current13:35, 22 June 2021Thumbnail for version as of 13:35, 22 June 20212,926 × 1,647 (694 KB)Guest2625 (talk | contribs)Uploaded a work by Makoto Ujike and Fumihiro Taguchi from Ujike, M.; Taguchi, F. Recent Progress in Torovirus Molecular Biology. Viruses 2021, 13, 435. https://doi.org/10.3390/v13030435 with UploadWizard

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