File:Serpin equilibrium.png
Jump to navigation
Jump to search
Size of this preview: 800 × 507 pixels. Other resolutions: 320 × 203 pixels | 640 × 406 pixels | 1,024 × 649 pixels | 1,280 × 812 pixels | 3,000 × 1,902 pixels.
Original file (3,000 × 1,902 pixels, file size: 1.41 MB, MIME type: image/png)
Captions
Captions
Add a one-line explanation of what this file represents
Summary[edit]
| Description |
English: The native state of serpins is an equilibrium between a fully-stressed state (left) and a partially relaxed state (right). The five-stranded A-sheet (light blue) contains two functionally important regions for the serpin's mechanism, the breach and the shutter. The Reactive Centre Loop (RCL, blue) exists in a dynamic equilibrium between the fully exposed conformation (left) and a conformation where it is partially inserted into the breach of the A-sheet (right). (PDB: 1QLP, 1YXA).
[1] [2] |
| Date | |
| Source | Own work |
| Author | Thomas Shafee |
Licensing[edit]
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- ↑ Elliott PR, Lomas DA, Carrell RW, Abrahams JP. (1996). "Inhibitory conformation of the reactive loop of alpha 1-antitrypsin". Nature Structural & Molecular Biology 3 (8): 676–81. DOI:10.1038/nsb0896-676. PMID 8756325.
- ↑ (2005). "The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.". J Biol Chem 280 (52): 43168–78. DOI:10.1074/jbc.M505598200. PMID 16141197.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 23:23, 6 October 2016 | | 3,000 × 1,902 (1.41 MB) | Cmdrjameson (talk | contribs) | Compressed with pngout. Reduced by 772kB (34% decrease). |
| 23:05, 19 March 2016 |  | 3,000 × 1,902 (2.16 MB) | Evolution and evolvability (talk | contribs) | Colour tweaks | |
| 12:05, 14 December 2015 |  | 1,246 × 765 (476 KB) | Evolution and evolvability (talk | contribs) | Cross-wiki upload from en.wikipedia.org |
You cannot overwrite this file.
File usage on Commons
The following 2 pages use this file:
File usage on other wikis
The following other wikis use this file:
