File:OXT and AVP synthesized in the neurons located in the PVN and SON.jpg
From Wikimedia Commons, the free media repository
Jump to navigation
Jump to search
Size of this preview: 800 × 411 pixels. Other resolutions: 320 × 165 pixels | 850 × 437 pixels.
Original file (850 × 437 pixels, file size: 257 KB, MIME type: image/jpeg)
File information
Structured data
Captions
Summary[edit]
DescriptionOXT and AVP synthesized in the neurons located in the PVN and SON.jpg |
English: Oxytocin (OXT) and arginine-vasopressin (AVP) are two closely related nonapeptides that exert their action on central and peripheral targets. (A) OXT and AVP are synthesized in the paraventricular nucleus (PVN) and the supraoptic nucleus (SON) of the hypothalamus. The peptidergic neurons in these nuclei project axons to the posterior pituitary, from where the peptides are released into the circulation. They act as hormones on peripheral targets, having well-documented actions (uterine contraction and vasoconstriction, for instance). In addition, dendrites of neurons in the PVN and the SON release the peptides directly into the brain, where they act as neurotransmitters or neuromodulators, regulating complex social cognition and behaviors. (B) OXT and AVP differ in only two aminoacids: this schematic drawing shows that, whereas the aminoacid sequence of OXT (top) includes an isoleucine at the third and a leucine at the eighth position, that of AVP (bottom) includes a phenylalanine and an arginine in the corresponding positions. Both peptides contain a cyclic six aminoacid ring, because of the disulfide bond formed by two cysteine residues. |
Date | |
Source | Aspé-Sánchez M, Moreno M, Rivera M-I, Rossi A and Ewer J (2016) Oxytocin and Vasopressin Receptor Gene Polymorphisms: Role in Social and Psychiatric Traits. Front. Neurosci. 9:510. doi: 10.3389/fnins.2015.00510 https://www.frontiersin.org/articles/10.3389/fnins.2015.00510/full |
Author | Mauricio Aspé-Sánchez, Macarena Moreno, Maria Ignacia Rivera, Alejandra Rossi and John Ewer |
Licensing[edit]
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 14:23, 16 September 2018 | 850 × 437 (257 KB) | Was a bee (talk | contribs) | {{Information |Description={{en|1=Oxytocin (OXT) and arginine-vasopressin (AVP) are two closely related nonapeptides that exert their action on central and peripheral targets. (A) OXT and AVP are synthesized in the paraventricular nucleus (PVN) and the supraoptic nucleus (SON) of the hypothalamus. The peptidergic neurons in these nuclei project axons to the posterior pituitary, from where the peptides are released into the circulation. They act as hormones on peripheral targets, having well-d... |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
File usage on other wikis
The following other wikis use this file:
- Usage on en.wikipedia.org
- Usage on es.wikipedia.org
- Usage on fr.wikibooks.org
Metadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Width | 6,378 px |
---|---|
Height | 3,543 px |
Bits per component |
|
Compression scheme | LZW |
Pixel composition | RGB |
Orientation | Normal |
Number of components | 3 |
Horizontal resolution | 72 dpi |
Vertical resolution | 72 dpi |
Data arrangement | chunky format |
Software used | Adobe Photoshop CS5.1 Windows |
File change date and time | 17:44, 18 January 2016 |
Color space | Uncalibrated |
Date and time of digitizing | 18:49, 9 November 2015 |
Date metadata was last modified | 23:14, 18 January 2016 |
Unique ID of original document | xmp.did:8898cd03-8bea-4387-9dd0-53e5b7d308b7 |