File:NFAT5 Osmotic Response Activation Pathway3.jpg

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NFAT5_Osmotic_Response_Activation_Pathway3.jpg(367 × 552 pixels, file size: 21 KB, MIME type: image/jpeg)

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English: Pathway of NFAT5-Mediated Osmotic Response Activation. Upon an osmotic stress signal, Brx, localized at the cell membrane, is activated and recruits JIP4, a p38 MAPK-specific scaffold protein. JIP4 binds to downstream kinases, MKK3 and MKK6, and activates p38 MAPK. p38 MAPK is necessary for naft5 expression.
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Author Mishat87

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current02:32, 9 June 2009Thumbnail for version as of 02:32, 9 June 2009367 × 552 (21 KB)Mishat87 (talk | contribs){{Information |Description={{en|1=Pathway of NFAT5-Mediated Osmotic Response Activation. Upon an osmotic stress signal, Brx, localized at the cell membrane, is activated and recruits JIP4, a p38 MAPK-specific scaffold protein. JIP4 binds to downstream kin

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