File:F24-03-9780123846846.png
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Deutsch: Schematic of the proposed life cycle of Emiliania huxleyi virus 86 (EhV-86). Enveloped EhV-86 enters E. huxleyi with an intact capsid and nucleoprotein core either by an endocytotic mechanism (step 1a) followed by fusion of its envelope with the vacuole membrane (step 2) or by fusion of its envelope with the host plasma membrane (step 1b). The viral capsid encapsulated nucleoprotein core rapidly targets the nucleus where capsid breakdown releases the viral genome (step 3). The viral genome enters the host nucleus where early promoter sequences are expressed by host RNA polymerase. Mid-late genes are expressed by viral RNA polymerase within the cytoplasm where capsid assembly takes place, possibly by filling of a pro-capsid with viral DNA and core proteins (step 4). Early assembled viruses are transported to the plasma membrane (step 5) where they are released by a budding mechanism (step 6). (from Mackinder et al. (2010). J. Gen. Virol., 90(9), 2306-2316; with permission). |
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Fig. 3 at https://talk.ictvonline.org/ictv-reports/ictv_9th_report/dsdna-viruses-2011/w/dsdna_viruses/124/phycodnaviridae-figures ICTV 9th Report (2011): Phycodnaviridae - Figures.  |
| Author | Wilson, W.H., Van Etten, J.L., Schroeder, D.C., Nagasaki, K., Brussaard, C., Bratbak, G. and Suttle, C. |
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