File:Estimated somatic mutation rates scaling with size.jpg
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English: Estimated somatic mutation rates scaling with size. Mutation rate estimates show that a 3.2-fold decrease enables an animal that is 1000× larger (and so with 1000× more stem cells) than a human to have the same cancer risk. The mutation rates shown in the plot resulted in cancer risk predictions for the given number of cells that best matched the estimates for human (i.e. 1.2 × 108 colonic stem cells) using the Calabrese–Shibata algebraic model. |
| Date | Published 8 June 2015 |
| Source | Aleah F. Caulin, Trevor A. Graham, Li-San Wang, Carlo C. Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis.Maley. Phil. Trans. R. Soc. B 2015 370 20140222; DOI: 10.1098/rstb.2014.0222. Published 8 June 2015 http://rstb.royalsocietypublishing.org/content/370/1673/20140222 |
| Author | Aleah F. Caulin, Trevor A. Graham, Li-San Wang, Carlo C |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 18:28, 4 August 2016 | | 1,280 × 724 (66 KB) | Was a bee (talk | contribs) | {{Information |Description={{en|1=Estimated somatic mutation rates scaling with size. Mutation rate estimates show that a 3.2-fold decrease enables an animal that is 1000× larger (and so with 1000× more stem cells) than a human to have the same cance... |
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