File:1-s2.0-S0041010113002390-gr3 (14244608529).jpg
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Description1-s2.0-S0041010113002390-gr3 (14244608529).jpg |
Source: Anita Malhotra , Simon Creer, John B. Harris, Reto Stöcklin, Philippe Favreau, Roger S. Thorpe (2013) Predicting function from sequence in a large multifunctional toxin family. Toxicon <a href="https://dx.doi.org/10.1016/j.toxicon.2013.06.019" rel="nofollow">dx.doi.org/10.1016/j.toxicon.2013.06.019</a> Published by Elsevier Fig. 3. A profile neighbour-joining (PNJ) tree of all Group II svPLA2 protein sequences illustrated as a radial cladogram. Branches have been colour coded according to the functional predictions derived from the DA, with colours corresponding to those used in Fig. 2. Thick lines represent proteins with a PP >80% of having that function, while thin lines represent 50% 80%. Black lines indicate proteins which had no clear assignment (PP>50%), or in the case of interior branches, where descendant sequences had multiple functions. Nodes marked by red circles represent those that are supported by bootstrap values > 50% in the final tree, while those marked by a purple circle represent sequences which have been united into a super-profile by several iterations of PNJ. Peripheral labels indicate the unique identifier of each protein and the species from which it was identified. Labels are coloured according to known (experimentally determined) functions. The outer circle indicates the position of two clades of Viperinae (true viper) sequences, which are clearly distinguished from all other PLA2s of crotaline (pit viper) origin. Labels A–F identify clusters that are supported by bootstrap values >50% and which are discussed in the text. |
Date | |
Source | 1-s2.0-S0041010113002390-gr3 |
Author | Phylogeny Figures |
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This image was originally posted to Flickr by phylofigures at https://flickr.com/photos/123636286@N02/14244608529. It was reviewed on 19 December 2020 by FlickreviewR 2 and was confirmed to be licensed under the terms of the cc-by-2.0. |
19 December 2020
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