File:University of Toronto studies. Physiological series. no. 1-98. 1900-28 (1900) (14793910683).jpg

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Identifier: universityoftor11univuoft (find matches)
Title: University of Toronto studies. Physiological series. no. 1-98. 1900-28
Year: 1900 (1900s)
Authors: University of Toronto
Subjects: Physiology
Publisher: (Toronto) University Library: Published by the Librarian
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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Fig. 5. Less prolonged intestinal constriction from a large dose of adrenalin(0.5 cc, 1: 10,000) in an older kitten than in the previous figure. Age eight weeks,weight 0.67 kgm. (Reduced ^.) eleven weeks of age gave active limb dilatation with adrenalin butabsolutely no intestmal dilatation. We may conclude from theseresults that the two mechanisms may begin to function at differentages in the same individual. Moreover in every case so far noted(three) the adrenalin vasodilator mechanism for the limb func-tioned earliest. These observations lend support to the idea that thetwo mechanisms are of different types. In conclusion we may ask: Why do the adrenalin vasodilator mech-anisms develop so late in the life of the individual? Does it mean thatthe mechanism is one of the last to appear in the evolution of the cat?If so, it might be that they are specialized mechanisms occurring 118 FRANK A. HARTMAN AND LESLIE G. KILBORN
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ADRENALIN VASODILATOR MECHANISMS IN CAT 119 only in the carnivora. (Their presence has been proven in the dog.)A systematic survey of the vertebrates for the presence of these mech-anisms is in progress in this laboratory. SUMMARY 1. The smallest effective doses of adrenalin produce only a rise inblood pressure in young kittens. 2. The threshold for adrenalin blood pressure effects is high in youngkittens, decreasing as they grow older. 3. The response to adrenalin of a fall in blood pressure begins to ap-pear at about eleven weeks. 4. The increasing of the depressor effects from the slight fall suc-ceeding a rise in younger animals to a marked almost pure fall inadults indicates a gradual development of the adrenalin vasodilatormechanism. 5. This fall in blood pressure seems to be due to vasodilatation inskeletal muscle, for the two begin to appear simultaneously in mostinstances. 6. The intestinal adrenalin vasodilator mechanism often developslater than the adrenalin vasodilator mec

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  • bookid:universityoftor11univuoft
  • bookyear:1900
  • bookdecade:1900
  • bookcentury:1900
  • bookauthor:University_of_Toronto
  • booksubject:Physiology
  • bookpublisher:_Toronto__University_Library__Published_by_the_Librarian
  • bookcontributor:Gerstein___University_of_Toronto
  • booksponsor:University_of_Toronto
  • bookleafnumber:119
  • bookcollection:gerstein
  • bookcollection:toronto
  • bookcollection:medicalheritagelibrary
  • BHL Collection
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