File:The origin of disease - especially of disease resulting from intrinsic as opposed to extrinsic causes - with chapters on diagnosis, prognosis, and treatment (1900) (14783357322).jpg

Identifier: originofdiseasee00meig (find matches)
Title: The origin of disease : especially of disease resulting from intrinsic as opposed to extrinsic causes : with chapters on diagnosis, prognosis, and treatment
Year: 1900 (1900s)
Authors: Meigs, Arthur V. (Arthur Vincent), 1850-1912
Subjects: Diseases Pathology
Publisher: Philadelphia : J.B. Lippincott
Contributing Library: Francis A. Countway Library of Medicine
Digitizing Sponsor: Open Knowledge Commons and Harvard Medical School

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nd is seen around two-thirds of the circuit. To the left,around the remaining third it has been destroyed, and the muscular coat and intima blendinto each other in such a manner that there is no sharp boundary between them. In thisregion the muscular coat is much thickened and the intima relatively less so, the effectbeing that the muscular layer comes nearer to the calibre of the vessel than at other por-tions of the circuit in which the plicated membrane still persists. The plicated membrane,if followed from light to left above, is seen to split into two layers before it disappears.There is great thickening of all the coats ; the muscular layer is irregularly thickened, andthe thickening of the intima is immense, as it constitutes the largest part of the vessel-wall : it must be remembered that in the natural condition the intima of arteries of thissize is only a thin layer of endothelial plates lying within the plicated membrane. (Com-pare with Fig. II.) -in. . :^^^^^^Sl^^4l Fig. 8
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^iomiu Fig. ii.—Obliterative Endarteritis. (X 55) From the same section as Fig. 10 : another artery. The calibre is greatly narrowed.The intima is enormously and irregularly thick, while the plicated membrane is most dis-tinct around the entire circuit. The muscular coat cannot be said to be thicker than nor-mal, but it is of irregular thickness, which is not natural. The two pictures demonstratethe irregular way in which the walls of arteries thicken so far as concerns the particularcoat which shall take on increase : in the one the increase is almost entirely of the intima;in the other the muscular layer has suffered as much as or more than the intima. Fig.ll

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