File:The origin of disease - especially of disease resulting from intrinsic as opposed to extrinsic causes - with chapters on diagnosis, prognosis, and treatment (1900) (14597035449).jpg

Identifier: originofdiseasee00meig (find matches)
Title: The origin of disease : especially of disease resulting from intrinsic as opposed to extrinsic causes : with chapters on diagnosis, prognosis, and treatment
Year: 1900 (1900s)
Authors: Meigs, Arthur V. (Arthur Vincent), 1850-1912
Subjects: Diseases Pathology
Publisher: Philadelphia : J.B. Lippincott
Contributing Library: Francis A. Countway Library of Medicine
Digitizing Sponsor: Open Knowledge Commons and Harvard Medical School

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ened that only a small irregularcalibre remains. The diseased intima, which is structurally connective tissue, is strikinglydifferent in appearance from the muscular coat. The latter is of very uneven thicknessand shades into the intima. No trace of the plicated membrane remains. Fig. 3.—Obliterative Endarteritis (Complete Closure of the Vessel). (X 60.) An arteriole in the fat covering the heart from a man of thirty years who died of organicheart disease. There is very little differentiation of coats. The muscularis is less closelyknit together than natural, and is not easily definable from the tissue filling the calibre.This is a loose-meshed fibrous material containing a number of small openings. Theseopenings are developing capillaries or cross-sections of cells of which the protoplasmfailed to stain. The object depicted might be thought not to be a vessel at all, but forthe fact that near it in the section there are others of similar appearance in various stagesof closure. FigJ
Text Appearing After Image:
2/o m m THE BLOOD-VESSELS. 39 evidence has as yet been forthcoming to demonstrate the real starting-point of fibroid disease. Various forms of arterial disease are illustrated by Figs. 1 to 17inclusive. Figs. 1, 2, and 3 show three stages of obliterative endar-teritis. Fig. 1 may be taken as a type of the commonest form of thedisease. The artery lies in the fatty covering of the heart from awoman forty years old who died of organic heart disease with nut-meg liver and increase of fibroid tissue in the spleen and kidneys. Inan artery of this size it might be expected, perhaps, that there wouldbe some subendothelial tissue between the innermost layer of endo-thelial cells and the plicated membrane, but the intima is unevenlythick,—a condition under all circumstances unnatural,—and even atthe point where it is thinnest it is at least four or five times thickerthan natural. When examined with a higher power, such tissue maybe at once recognized as pathological. The plicated membrane i

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