File:The elements of pathological histology with special reference to practical methods (1895) (14770931881).jpg

Identifier: elementsofpathol00weic (find matches)
Title: The elements of pathological histology with special reference to practical methods
Year: 1895 (1890s)
Authors: Weichselbaum, Anton, 1845- Dawson, W. R., tr
Subjects: Histology, Pathological Histology Pathology
Publisher: London : Longmans
Contributing Library: Francis A. Countway Library of Medicine
Digitizing Sponsor: Open Knowledge Commons and Harvard Medical School

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either restricts itself to the vessel-sheaths, orattacks the actual nervous substance. Syphilis occurs not only in the brain and spinal cord themselves,but in the meninges and the nerves issuing from them, taking onthe one hand the form of gummata, on the other that of syphiliticvasculitis. As the gummata usually attain a more considerable size,especially in the brain, parts as a rule are found in them which are 348 THE CENTRAL NERVOUS SYSTEM already more or less caseated (Fig. 173, c), and in the immediateneighbourhood of which the tissue of the syphiloma consists entirelyor at least partially of spindle cells, whereas in all other places itis composed exclusively of round cells. Isolated giant cells (b) mayalso be found. It is not uncommon to meet with gummata andsyphilitic vasculitis side by side. Amongst the nevj-formations of the brain and spinal cord, theglioma and the ganglionic neuroglioma must be mentioned. Theformer (Fig. 174) usually occurs as a diffuse growth, which either
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Fia. 173. -Gumma Cerebri, x 285. (Haematoxylin and eosin.) a, Round and spindle-shaped cells ; (>, Giant cell; c, Caseous portions. resembles the normal neuroglia, i.e., contains relatively few and smallcells, provided with numerous processes, in an interstitial substanceof line fibres (b); or is composed, after the fashion ^f a sarcoma, ofdensely-packed cells of larger size, in which latter case we may speakof it as a glio-sarcoma. Besides this, pnre sarcomata also occur, andthese as well as the gliomata are frequently very vascular, and shownumerous hiiemorrhages. In the gliomata softening, liquefaction, andformation of cavities (d) may also result. Should nerve-fibres alsoexist in a glioma (c), the latter forms a transition stage to the NEW GROWTHS 349 ganglionic neuroglioma, which differs from the simple glioma in con-taining in its glia-like tissue ganglion cells of variable size, andmedullated and perhaps also non-medullated nerve-fibres. The new-formations in the inner menin

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