File:TIM and LDH vs schematics.png
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DescriptionTIM and LDH vs schematics.png |
English: Two of the commonest protein "folds" in 3D, each illustrated by a very simplified schematic diagram (at right) of the course of the polypeptide chain, and by a ribbon drawing of the classic example protein (at left).
Drawings made by Jane S. Richardson during 1980, and composited 2016-02-04.First (top) is the fold called a "TIM barrel", (beta/alpha)8 barrel, or "singly-wound" barrel, with a central cylinder of 8 parallel beta strands, adjacent strands connected by righthanded beta-alpha-beta loops. Triose phosphate isomerase (TIM) is the classic example. Second (below) is the fold called a nucleotide-binding domain, a "Rossmann fold", or a "doubly-wound" parallel beta domain, with a central, twisted sheet of parallel beta strands, The chain starts at bottom center, winds to the right with beta-alpha-beta loops (black half in ribbon drawing), then switches back to the center and winds to the left. Lactate dehydrogenase (LDH) domain 1 is the classic example |
Date | |
Source | Own work |
Author | Dcrjsr |
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current | 21:04, 5 October 2016 | 1,320 × 1,340 (442 KB) | Cmdrjameson (talk | contribs) | Compressed with pngout. Reduced by 440kB (49% decrease). | |
16:20, 10 February 2016 | 1,320 × 1,340 (883 KB) | Dcrjsr (talk | contribs) | User created page with UploadWizard |
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