File:SOC001.jpg

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The formation of endochondral ossification and articular cartilage.

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Description
English: The formation of endochondral ossification and articular cartilage. Initially, mesenchymal cells undergo agglutination, mesenchymal cells in the center differentiate into chondrocytes and secrete type II collagen, chondrocytes continue to proliferate and secrete ECM, and cells around the agglutination express type I collagen and become cartilage membrane. The cartilage center’s cells then transform into hypertrophic chondrocytes, and blood vessels invade and create main ossification centers. Cartilage is progressively replaced by bone, and the cartilage membrane transforms into periosteum. At the ends of the elements, secondary ossification centers are created, and the epiphyseal cartilage plate is generated between the secondary and primary ossification centers. At last, the epiphyseal plate ossifies, leaving permanent articular cartilage at the element’s end.
Date
Source https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570753/
Author Zhanpeng Su, Zhixian Zong, Jinxia Deng, Jianping Huang, Guihua Liu, Bo Wei, Liao Cui, Gang Li, Huan Zhong, and Sien Lin

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Date/TimeThumbnailDimensionsUserComment
current05:18, 15 January 2024Thumbnail for version as of 05:18, 15 January 20241,072 × 928 (221 KB)PecMo (talk | contribs)Removed another corner issue. Sorry for the multiple uploads.
05:15, 15 January 2024Thumbnail for version as of 05:15, 15 January 20241,080 × 928 (224 KB)PecMo (talk | contribs)Removed the green corners.
05:07, 15 January 2024Thumbnail for version as of 05:07, 15 January 20241,080 × 928 (226 KB)PecMo (talk | contribs)Uploaded a work by Zhanpeng Su, Zhixian Zong, Jinxia Deng, Jianping Huang, Guihua Liu, Bo Wei, Liao Cui, Gang Li, Huan Zhong, and Sien Lin from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570753/ with UploadWizard

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