File:PCA of Nepalese and neighbouring populations.png
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| Description |
English: Principal component analysis (PCA) to provide a broad overview of population structure across the Himalaya. Four broad population clusters were apparent; 1) a ‘northern Himalayan’ cluster consisting of Han Chinese, Tibetans and the Sherpa, 2) A ‘northwestern’ cluster consisting of populations of the Pamir mountain range, 3) a ‘southwestern’ cluster consisting of Pakistani and Indian populations and 4) a ‘central Himalayan’ cluster consisting of the Nepalese. Genes mirror the geography of the greater Himalayan region. PC1 and PC2 explain genetic distance between populations as directions of variance. This was performed on a thinned dataset of 34,253 SNPs. Each dot represents an individual in the dataset. Each population is represented by a shape, Tibetans (X), Sherpa (★), Han (O), Nepalese (•), Indian (+), Pakistan (Δ) and the Pamir populations (□). Each of the Indian ancestral groups as described in Basu et al., 2016, are indicated as follows; [] ANI, + ASI, * AAA, ** ATB. The Nepalese appear as an admixed population between the northern Himalayan cluster (Tibet, Sherpa and Han) and the southern Himalayan cluster (India and Pakistan), with clear genetic variance between ethnic subgroups. |
| Date | Published: 19 January 2017 |
| Source | Cole, A.M., Cox, S., Jeong, C. et al. Genetic structure in the Sherpa and neighboring Nepalese populations. BMC Genomics 18, 102 (2017). https://doi.org/10.1186/s12864-016-3469-5 |
| Author | Amy M. Cole, Sean Cox, Choongwon Jeong, Nayia Petousi, Dhana R. Aryal, Yunden Droma, Masayuki Hanaoka, Masao Ota, Nobumitsu Kobayashi, Paolo Gasparini, Hugh Montgomery, Peter Robbins, Anna Di Rienzo & Gianpiero L. Cavalleri |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 12:05, 31 January 2021 | | 1,100 × 913 (419 KB) | Was a bee (talk | contribs) | {{Information |Description={{en|1=Principal component analysis (PCA) to provide a broad overview of population structure across the Himalaya. Four broad population clusters were apparent; 1) a ‘northern Himalayan’ cluster consisting of Han Chinese, Tibetans and the Sherpa, 2) A ‘northwestern’ cluster consisting of populations of the Pamir mountain range, 3) a ‘southwestern’ cluster consisting of Pakistani and Indian populations and 4) a ‘central Himalayan’ cluster consisting of the Nepalese.... |
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