File:Methotrexate-3D-balls-1U72.png

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Description Ball-and-stick model of methotrexate, as bound to human dihydrofolate reductase. Hydrogen atoms omitted for clarity.
Created using Accelrys DS Visualizer Pro 1.7 and GIMP. Optimized with OptiPNG.
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Source

From PDB 1u72. More information:

  • Cody V, Luft JR, Pangborn W (February 2005). "Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH". Acta Crystallogr. D Biol. Crystallogr. 61 (Pt 2): 147–55. PMID 15681865. doi:10.1107/S0907444904030422
Author Fvasconcellos (talk · contribs)
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Public domain I, the copyright holder of this work, release this work into the public domain. This applies worldwide.
In some countries this may not be legally possible; if so:
I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law.

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Date/TimeThumbnailDimensionsUserComment
current01:34, 26 July 2008Thumbnail for version as of 01:34, 26 July 20081,200 × 1,305 (220 KB)Fvasconcellos (talk | contribs){{Information |Description= |Source= |Date= |Author= |Permission= |other_versions= }}
01:17, 26 July 2008Thumbnail for version as of 01:17, 26 July 20081,200 × 1,305 (215 KB)Fvasconcellos (talk | contribs)optimized with OptiPNG
01:16, 26 July 2008Thumbnail for version as of 01:16, 26 July 20081,200 × 1,305 (216 KB)Fvasconcellos (talk | contribs)== Summary == {{Information |Description= {{w|Ball-and-stick model}} of {{w|methotrexate}}, as bound to human {{w|dihydrofolate reductase}}. Hydrogen atoms omitted for clarity.<br />Created using [http://www.accelrys.com/products/downloads/ds_visualizer/

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