File:Manhattan plots for the skin hair eye pigmentation.png
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English: Manhattan plots for the GWAS results for the skin (A), hair (B), and eye (C) pigmentation. The log-transformed p-values from the test of association are plotted as a function of the chromosomal position. Genome-wide significance is defined as the Bonferroni corrected 5% significance threshold (p-value<1.6×10−7) and is indicated as a red line. For skin pigmentation, one SNP on chromosome 3 in the FLNB gene almost reaches genome-wide significance (p-value = 1.8×10−7). No SNP achieves genome-wide significance in the hair pigmentation GWAS. For eye pigmentation, two SNPs, one near the pigmentation gene OCA2 on chromosome 15 and one in the SCIN gene on chromosome 7 achieve genome-wide significance |
| Date | |
| Source | Candille SI, Absher DM, Beleza S, Bauchet M, McEvoy B, Garrison NA, et al. (2012) Genome-Wide Association Studies of Quantitatively Measured Skin, Hair, and Eye Pigmentation in Four European Populations. PLoS ONE 7(10): e48294. doi:10.1371/journal.pone.0048294 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048294 |
| Author | Sophie I. Candille , Devin M. Absher, Sandra Beleza, Marc Bauchet, Brian McEvoy, Nanibaa’ A. Garrison, Jun Z. Li, Richard M. Myers, Gregory S. Barsh, Hua Tang , Mark D. Shriver |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 22:02, 11 April 2016 | | 1,495 × 1,974 (1.1 MB) | Was a bee (talk | contribs) | {{Information |Description={{en|1=Manhattan plots for the GWAS results for the skin (A), hair (B), and eye (C) pigmentation. The log-transformed p-values from the test of association are plotted as a function of the chromosomal position. Genome-wide si... |
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