File:Loss of heterozygosity.PNG

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Loss_of_heterozygosity.PNG(687 × 448 pixels, file size: 9 KB, MIME type: image/png)

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Description Loss of heterozygosity means that the another allele of the gene is lost. Then only already mutated allele is left. M=maternal chromosome, P=paternal chromosome. White circle=normal allele, black circle=mutated allele, orange circle=point mutation in the allele, red circle=allele is inactivated due to the epigenetic reason. Arrows show different malicious genetic happenigs. In A-C cases the loss of heterozygosity of the gene has happened and mechanisms are different. A=The another chromosome has been lost, B=The malicious recombination has happened and C=The deletion of the normal allele has happened. In D and E cases both alleles have been inactivated, but the heterozygosity remains.
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Author Teemu Pelkonen
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current13:13, 14 May 2008Thumbnail for version as of 13:13, 14 May 2008687 × 448 (9 KB)Teemu Pelkonen~commonswiki (talk | contribs){{Information |Description=Loss of heterozygosity means that the another allele of the gene is lost. Then only already mutated allele is left. M=maternal chromosome, P=paternal chromosome. White circle=normal allele, black circle=mutated allele, orange ci

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