File:Freezing microtome, London, England, 1883-1885 Wellcome L0058209.jpg

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Freezing microtome, London, England, 1883-1885
Title
Freezing microtome, London, England, 1883-1885
Description

Invented in 1881, this type of freezing microtome used ice and salt to freeze animal and plant specimens to be sliced for microscope slides. Ice and salt were replaced by a removable ether spray in 1883. Freezing hardened and preserved the specimens’ structure quickly. Chemical preservation usually took six weeks but by using ether the process took a matter of seconds. Once frozen, a razor, operated by hand and secured by a tripod, moved across the top of specimen, creating slices. The slices were then mounted, stained and studied under the microscope by histologists. The knife and tubing is missing.

modifier: Fearnley, W., maker: James Swift and Son

Place made: London, Greater London, England, United Kingdom

Wellcome Images
Keywords: freezing microtome; valentin knife; ether; Histology

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This file comes from Wellcome Images, a website operated by Wellcome Trust, a global charitable foundation based in the United Kingdom. Refer to Wellcome blog post (archive).
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References
  • Library reference: Science Museum A627272
  • Photo number: L0058209
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https://wellcomeimages.org/indexplus/obf_images/f5/6b/7bb24bde4ee8e5fd32fc1f84b798.jpg

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current12:38, 17 October 2014Thumbnail for version as of 12:38, 17 October 20144,256 × 2,832 (1.25 MB) (talk | contribs)=={{int:filedesc}}== {{Artwork |artist = |author = |title = Freezing microtome, London, England, 1883-1885 |description = Invented in 1881, this type of freezing microtome used ice and salt to freeze animal a...

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