File:Fpls-02-00039-g007.png

English: Models of leaf metabolism during early interaction stages. Based on the results of the combined metabolome and transcriptome analysis, models illustrating the reprogramming of host metabolism during early biotrophic interactions are depicted for Bgh infected barley leaves at 24hpi (A), Cg infected maize leaves at 36hpi (B) and Um infected maize leaves at 48hpi (C). Please note that for simplicity, C4 metabolism has been omitted from the maize models. Yellow – up compared to mock control; blue – down compared to mock control. Arrow thickness correlates with the proposed metabolic flux relative to the other depicted metabolic pathways. For explanations, please see the discussion text. Amino acids are abbreviated according to three letter code, 2PG, (2-phosphoglycolate); aKG, (α-ketoglutarate) Hex (hexoses); Icit, (isocitrate); PEP, (phosphoenol pyruvate); 3-PGA, (3-phosphoglycerate); Suc, (sucrose); TP (triose phosphates); αKG-DH, (α-ketoglutarate dehydrogenase); AK, (aspartate kinase); AsnS, (asparagine synthetase); CitS, (citrate synthase); cw-INV, (cell wall invertase); DCT2, (dicarboxylate translocator); FBPase2, (fructose-2,6-bisphosphatase); IDH, (isocitrate dehydrogenase); IPMS, (isopropylmalate synthase); MDH, (malate dehydrogenase); PEPC, (PEP carboxylase); PFK2, (phosphofructokinase 2); PFP, (pyrophosphate-dependent phosphofructokinase); PPT, (phosphoenolpyruvate/phosphate translocator); SHMT, (serine hydroxymethyl transferase); SPS, (sucrose phosphate synthase); SuSy, (sucrose synthase).