File:Fphar-14-1294966-g003 (1).webp
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Fphar-14-1294966-g003_(1).webp (726 × 509 pixels, file size: 35 KB, MIME type: image/webp)
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DescriptionFphar-14-1294966-g003 (1).webp |
English: FIGURE 3. Mechanism of action of reverse transcriptase inhibitors. Reverse transcriptase inhibitors are classified into NRTIs and NNRTIs. The virus enters the host cell, sheds its capsid, and exposes genetic material. Cellular kinases phosphorylate the NRTIs and bind competitively with dNTP to template RNA, which blocks the transcription of viral genes. In contrast, NNRTIs bind to hydrophobic pockets close to the RT active site and inhibit viral gene transcription (Maga et al., 2010). Created with BioRender.com. |
Date | |
Source | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1294966/full |
Author | Peng Y, Zong Y, Wang D, Chen J, Chen ZS, Peng F, Liu Z. |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 18:16, 11 April 2024 | 726 × 509 (35 KB) | Ozzie10aaaa (talk | contribs) | better quality | |
18:10, 11 April 2024 | 290 × 203 (8 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Peng Y, Zong Y, Wang D, Chen J, Chen ZS, Peng F, Liu Z. from https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1294966/full with UploadWizard |
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