File:Fped-06-00058-g003 (1).jpg
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Nephropathic Cystinosis
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| Description |
English: FIGURE 3. Intracellular cystine metabolism. Cystine normally leaves the lysosome via cystinosin by cystine-proton symport (yellow arrows). Mutations in the CTNS gene cause cystine accumulation in the lysosome due to dysfunction of cystinosin (black arrows). Cystin accumulates and forms crystals inside the lysosome. Cysteamine induces a chemical reaction resulting in cysteamine–cysteine and cysteine. Both molecules exit the lysosome bypassing the cystinosin transporter protein (green arrows). Adapted from Ref. (6). |
| Date | |
| Source | https://www.frontiersin.org/articles/10.3389/fped.2018.00058/full |
| Author | Sören Bäumner,Lutz T. Weber |
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| current | 21:48, 27 January 2024 | | 758 × 449 (164 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Sören Bäumner,Lutz T. Weber from https://www.frontiersin.org/articles/10.3389/fped.2018.00058/full with UploadWizard |
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