File:Fluorescence Imaging 06.jpg
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Deutsch: Die Anreicherung von STL-6014, einem Bakteriochlorophyll (BChl), das mit einer RGD-Sequenz konjugiert wurde, im nekrotischen Gewebe eines orthotopen Brustkrebstumors vom Typ MDA-MB-231-RFP, der in eine weibliche CD-1-Nacktmaus implantiert wurde. 15 mg/kg KGW STL-6014 wurde intravenös appliziert. Die Aufnahme entstand vier Stunden nach der STL-6014-Injektion. Die Aufnahme ist ein Fusionsbild aus NIR- und SW-Tageslichtaufnahme.
English: STL-6014 accumulation in the necrotic area of large orthotopic MDA-MB-231-RFP tumors. CD-1 nude, female mice (n 3) bearing an orthotopically grafted, large MDA-MB-231-RFP tumor were intravenously injected with 15 mg/kg STL-6014. (NIR) fluorescence images for detection of STL-6014 distribution. |
| Date | published 24 May 2010 |
| Source | Liat Goldshaid, Efrat Rubinstein, Alexander Brandis, Dadi Segal, Noa Leshem, Ori Brenner, Vyacheslav Kalchenko, Doron Eren, Tamar Yecheskel, Yoseph Salitra, Yoram Salomon and Avigdor Scherz: Novel design principles enable specific targeting of imaging and therapeutic agents to necrotic domains in breast tumors. In: Breast Cancer Research 2010, 12:R29doi:10.1186/bcr2579 Open Access |
| Author | Liat Goldshaid, Efrat Rubinstein, Alexander Brandis, Dadi Segal, Noa Leshem, Ori Brenner, Vyacheslav Kalchenko, Doron Eren, Tamar Yecheskel, Yoseph Salitra, Yoram Salomon and Avigdor Scherz |
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| current | 17:42, 23 June 2010 | | 686 × 859 (178 KB) | Kuebi (talk | contribs) | {{Information |Description={{de|Die Anreicherung von STL-6014, einem Bakteriochlorophyll (BChl), das mit einer RGD-Sequenz konjugiert wurde, im nekrotischen Gewebe eines orthotopen Brustkrebstumors vom Typ MDA-MB-231-RFP, der in eine weibliche CD-1-Nacktm |
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