File:Doi.10.1128.JVI.00175-20.F8.large.jpg

English: Structural comparisons of the Mononegavirales RNA polymerases. The active sites of the RdRp and Cap domains of L, GDN, and HR are shown in magenta spheres and sticks, respectively. The priming loops and supporting helix are colored in orange. (A) The structural superimposition of the Rhabdoviridae L. The VSV L is colored the same as Fig. 3A, and the RABV L is colored in gray. (B) The structural superimposition of the Rhabdoviridae P. The VSV P is colored in magenta the same as Fig. 3A, and the RABV P is colored in brown. Only the interacting domains RdRp, CD, and CTD of L are shown as surface. (C) The structural superimposition of the Pneumoviridae L. The HRSV L is colored the same as Fig. 4A, and the HMPV L is colored in gray. Note that the supporting helix is missing. (D) The superimposition of the Pneumoviridae P. The HRSV P is colored the same as Fig. 4A, and the HMPV P is colored in brown. Only the interacting domain RdRp of L is shown as surface. (E) The structural representation of the Paramyxoviridae L. The HPIV L is colored the same as Fig. 5A. (F) The location of the Paramyxoviridae P. The HPIV P is colored the same as Fig. 5A. Only the interacting domain RdRp of L is shown as surface. The PDB accession codes are underlined.