File:Diacylglycerol lipase's hydrolysis mechanism producing 2-arachidonoylglycerol.png

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English: Diacylglycerol lipase is a serine hydrolase that uses the Ser-His-Asp catalytic triad to hydrolyze a diacylglycerol to a monoacylglycerol and a fatty acid. Here the substrate is 1-stearoyl-2-arachidonoyl-sn-glycerol and the products are stearic acid and 2-arachidonoylglycerol. The mechanism is notable for have a tetrahedral intermediate that allows the displacement of the stearic acid with a hydroxyl group.


Mechanism diagram produced in ChemDraw 22.0.0.
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Source Own work
Author Zhazhir

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current22:55, 1 March 2023Thumbnail for version as of 22:55, 1 March 20238,507 × 6,029 (1.86 MB)Zhazhir (talk | contribs)Uploaded own work with UploadWizard

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