File:Choline metabolism.svg

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search

Original file ‎(SVG file, nominally 650 × 690 pixels, file size: 5 KB)

Captions

Captions

Add a one-line explanation of what this file represents

Summary[edit]

Description
English: Main pathways of choline (Chol) metabolism, synthesis and excretion.

All of the substrates and products of PC→Chol, 3PG→PE and DimethylGly→Glycine are not shown.

Black: main substrates/products

  • 3PG: 3-phosphoglycerate
  • CDP-Chol: cytidine diphosphate-choline
  • Chol: choline
  • xGly: methylglycine (sarcosine), dimethylglycine and trimethylglycine (betaine)
  • GlyBA: glycine betaine aldehyde
  • HCys: homocysteine
  • PC: phosphatidylcholine
  • PChol: phosphocholine
  • PE: phosphatidylethanolamine
  • SAH: S-adenosylhomocysteine
  • SAM: S-Adenosyl methionine

Gray: side substrates/cofactors/other

  • ADP: adenosine diphosphate
  • ATP: adenosine triphosphate
  • B12: cobalamin
  • CMP: cytidine monophosphate
  • CTP: cytidine triphosphate
  • CoA: (acetyl-)coenzyme A
  • DAG: diglyceride
  • NADH: nicotinamide adenine dinucleotide
  • PPi: pyrophosphate
  • THF: (methyl-)tetrahydrofolate

Red: enzymes

  • BADH: betaine-aldehyde dehydrogenase, EC 1.2.1.8
  • BHMT: betaine-homocysteine S-methyltransferase, EC 2.1.1.5
  • CK: choline kinase, EC 2.7.1.32
  • CPCT: choline-phosphate cytidylyltransferase, EC 2.7.7.15
  • CPT: diacylglycerol cholinephosphotransferase, EC 2.7.8.2
  • ChAT: choline acetyltransferase, EC 2.3.1.6
  • ChOx: choline oxidase, EC 1.1.3.17
  • MS: methionine synthase, EC 2.1.1.13
  • PEMT: phosphatidylethanolamine N-methyltransferase, EC 2.1.1.17
  • PLs: phospholipases
  • SAHase: adenosylhomocysteinase, EC 3.3.1.1

Purple: PEMT pathway

Blue: CDP-choline pathway

Adapted from (with added details):

Date
Source Own work
Author 5-HT2AR

Licensing[edit]

I, the copyright holder of this work, hereby publish it under the following license:
Creative Commons CC-Zero This file is made available under the Creative Commons CC0 1.0 Universal Public Domain Dedication.
The person who associated a work with this deed has dedicated the work to the public domain by waiving all of their rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. You can copy, modify, distribute and perform the work, even for commercial purposes, all without asking permission.

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current21:38, 22 October 2019Thumbnail for version as of 21:38, 22 October 2019650 × 690 (5 KB)5-HT2AR (talk | contribs)User created page with UploadWizard

You cannot overwrite this file.

There are no pages that use this file.

File usage on other wikis

The following other wikis use this file:

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:Choline_metabolism.svg&oldid=857585986"