File:Cell flow patterns during streak formation for different mechanisms.jpg

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Figure 7. Cell flow patterns during streak formation for different mechanisms.

Our four models (M1)–(M4) for cell attraction and repulsion and four models of growth and induced polarization produce sixteen possible sets of combined mechanisms. (Left) Typical cell patterns at 7000 time steps beginning from Fig. 3D and (Right) Corresponding cell-flow velocity fields for each case. In the absence of proliferation, limited, local vortical motion occurs without induced polarization. However, large-scale vertical motion requires induced polarization. Chemorepulsion mechanisms (mechanism M2, ST repels AP) and (mechanism M3, S repels ST) produce the most robust streak/streak tip structures. Simulations generated using CompuCell3D. For parameters, see Supplementary Materials Table S1
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010571 Modeling Gastrulation in the Chick Embryo: Formation of the Primitive Streak. PLOS ONE 5(5):e10571. https://doi.org/10.1371/journal.pone.0010571 Editor: Nick Monk, University of Nottingham, United Kingdom
Copyright: © 2010 Vasiev et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source

are credited.
Author Vasiev B, Balter A, Chaplain M, Glazier JA, Weijer CJ

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current21:13, 11 April 2024Thumbnail for version as of 21:13, 11 April 20241,929 × 1,046 (1.7 MB)Rasbak (talk | contribs){{information |description=Figure 7. Cell flow patterns during streak formation for different mechanisms.<br> Our four models (M1)–(M4) for cell attraction and repulsion and four models of growth and induced polarization produce sixteen possible sets of combined mechanisms. (Left) Typical cell patterns at 7000 time steps beginning from Fig. 3D and (Right) Corresponding cell-flow velocity fields for each case. In the absence of proliferation, limited, local vortical motion occurs without induc...

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