File:Catalytic mechanisms of Topoisomerases.jpg
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DescriptionCatalytic mechanisms of Topoisomerases.jpg |
English: Summary of topoisomerase types and catalytic mechanisms. The topoisomerases are categorised based on whether they catalyse single- (type I) or double-stranded (type II) DNA breaks. The type I topoisomerases are further subdivided to type IA, IB and IC. Type IA form a transient covalent bond to the 5ʹ DNA phosphate and function via a strand passage mechanism. Type IB and IC form a transient covalent bond to the 3ʹ DNA phosphate and function via a controlled-rotation mechanism. Type II topoisomerases are further subdivided into type IIA and IIB. Both form a transient covalent bond to the 5ʹ DNA phosphate of both strands of the duplex and function via a strand-passage mechanism |
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Source | Own work |
Author | Kcneuman |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 06:11, 10 April 2022 | 1,841 × 444 (250 KB) | Kcneuman (talk | contribs) | Uploaded own work with UploadWizard |
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Orientation | Normal |
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Horizontal resolution | 300 dpi |
Vertical resolution | 300 dpi |
Software used | Adobe Photoshop 23.2 (Windows) |
File change date and time | 22:38, 9 April 2022 |
Color space | Uncalibrated |
Date and time of digitizing | 04:07, 20 November 2020 |
Date metadata was last modified | 18:38, 9 April 2022 |
Unique ID of original document | xmp.did:97eb264a-a86f-3a43-ac05-83230856d4f2 |
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20 November 2020
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d39e906fac5c3c16e3637b88f2a6e237b6188337
256,351 byte
444 pixel
1,841 pixel
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