File:CRISPR-Cas9 mode of action - ru.svg

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search

Original file ‎(SVG file, nominally 1,551 × 442 pixels, file size: 116 KB)

Captions

Captions

Add a one-line explanation of what this file represents

Summary[edit]

Description
English: A duplex of crRNA and tracrRNA acts as guide RNA to introduce a specifically located gene modification based on the RNA 5’ upstream of the crRNA. Cas9 binds the tracrsRNA and needs a DNA binding sequence (5’NGG3’), which is called protospacer adjacent motif (PAM). After binding, Cas9 introduces a DNA double strand break, which is then followed by gene modification via homologous recombination (HDR) or non-homologous end joining (NHEJ).
Русский: Дуплекс crРНК и tracrРНК работает как направляющая РНК, которая привлекает Cas9 к специфическому сайту в молекуле-мишени. Для распознавания мишени Cas9 необходимо, чтобы она содержала последовательность РАМ (5'-NGG-3' в случае Cas9).
Date
Source File:CRISPR-Cas9 mode of action.png by ViktoriaAnselm
Author Kaidor
Permission
(Reusing this file)
This work is ineligible for copyright and therefore in the public domain because it consists entirely of information that is common property and contains no original authorship.
I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
attribution share alike
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
Other versions
  • English PNG
    English PNG
SVG development
InfoField
 
The SVG code is valid.
 
This vector image was created with Inkscape, or with something else.
Graphic Lab
This image was improved or created by the Wikigraphists of the Graphic Lab (ru). You can propose images to clean up, improve, create or translate as well.

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current19:09, 20 February 2016Thumbnail for version as of 19:09, 20 February 20161,551 × 442 (116 KB)Kaidor (talk | contribs)User created page with UploadWizard

You cannot overwrite this file.

File usage on other wikis

The following other wikis use this file:

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:CRISPR-Cas9_mode_of_action_-_ru.svg&oldid=844741940"