File:Acción de receptores nucleares II.png

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English: Created myself using CambridgeSoft BioDraw. Mechanism nuclear receptor action. This figure depicts the mechanism of a class II nuclear receptor (NR) which, regardless of ligand binding status is located in the nucleus bound to DNA. For the purpose of illustration, the nuclear receptor shown here is the thyroid hormone receptor (TR) heterodimerized to the RXR. In the absence of ligand, the TR is bound to corepressor protein. Ligand binding to TR causes a dissociation of corepressor and recruitment of coactivator protein which in turn recruit additional proteins such as RNA polymerase that are responsible for transcription of downstream DNA into RNA and eventually protein which results in a change in cell function.
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This is a retouched picture, which means that it has been digitally altered from its original version. Modifications: Traducción. The original can be viewed here: Type ii nuclear receptor action.png: . Modifications made by Gonn.


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  • File:Type_ii_nuclear_receptor_action.png licensed with PD-self
    • 2008-11-30T11:17:09Z Boghog2 2999x2249 (1038926 Bytes) {{Information |Description={{en|1=Created myself using CambridgeSoft BioDraw. Mechanism nuclear receptor action. This figure depicts the mechanism of a class II nuclear receptor (NR) which, regardless of ligand binding statu

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current19:46, 8 February 2010Thumbnail for version as of 19:46, 8 February 20101,502 × 1,129 (537 KB)Gonn (talk | contribs){{Information |Description={{en|1=Created myself using CambridgeSoft BioDraw. Mechanism nuclear receptor action. This figure depicts the mechanism of a class II nuclear receptor (NR) which, regardless of ligand binding status is located in the nucleus bo

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