File:AIR Synthetase.svg

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English: AIR synthetase is the fifth enzyme in the de novo synthesis of purine nucleotides. It catalyzes the reaction to form 5-aminoimidizole ribonucleotide (AIR) from formylglycinamidine-ribonucleotide FGAM. This reaction closes the ring and produces a 5-membered imidazole ring of the purine nucleus (AIR).

The reaction is:

ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine {FGAM} → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole {AIR} + phosphate + H+

 
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Author J3D3

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Date/TimeThumbnailDimensionsUserComment
current18:53, 11 February 2022Thumbnail for version as of 18:53, 11 February 2022535 × 131 (44 KB)J3D3 (talk | contribs)Neutral forms.
19:07, 8 February 2022Thumbnail for version as of 19:07, 8 February 2022535 × 131 (43 KB)J3D3 (talk | contribs)Oxigen
18:43, 8 February 2022Thumbnail for version as of 18:43, 8 February 2022474 × 134 (31 KB)J3D3 (talk | contribs)added missing methylene bridge, rescaled, margins
23:41, 8 August 2014Thumbnail for version as of 23:41, 8 August 2014456 × 139 (27 KB)J3D3 (talk | contribs)User created page with UploadWizard

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